Thursday, October 31, 2013

Katy Perry Sends "Love and Light" to Olivia Wise

In response to a beautiful and heart-wrenching cover of her brand new single, "Roar," superstar singer Katy Perry sent a video recording encouraging Olivia Wise, a fan with brain cancer, to "keep roaring."


Olivia is a teen from Toronto, whose cover of "Roar" has taken the world by storm. Katy began her shout out by saying, "I just wanted to reach back out to you and tell you that I saw your video and I was very moved, and you sounded great for being in the studio and making it your wish to record that song. I thought that was really cool."


The 29-year-old went on: "I love you and a lot of people love you, and that's why your video got to me and moved everybody that saw it. So I just wanted to send you some love and some light and tell you that I'm thinking about you. Thank you so much. Keep roaring."


Olivia brought courage and strength to the mic, as she sang the hit song without flaw, accompanied by the song's soft piano and powerful melody. Her cousin, Jeff Kassel reportedly arranged the session with his friend, California-based music producer Jon Levine.


Kassel told the Toronto Star that their entire family has been blown away by the positive response the song had garnered. Watch below, and listen for yourself!




Source: http://celebrity-gossip.net/katy-perry/katy-perry-sends-love-and-light-olivia-wise-952607
Tags: chris brown   burn notice   powerball numbers   Lady Gaga   Katy Perry Roar  

Wednesday, October 30, 2013

Absence of the SMG1 protein could contribute to Parkinson's and other neurological disorders

Absence of the SMG1 protein could contribute to Parkinson's and other neurological disorders


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Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute



TGen-led study links lack of SMG1 to protein aggregates associated with Parkinson's disease, forms of dementia and multiple systems atrophy



PHOENIX, Ariz. Oct. 30, 2013 The absence of a protein called SMG1 could be a contributing factor in the development of Parkinson's disease and other related neurological disorders, according to a study led by the Translational Genomics Research Institute (TGen).


The study screened 711 human kinases (key regulators of cellular functions) and 206 phosphatases (key regulators of metabolic processes) to determine which might have the greatest relationship to the aggregation of a protein known as alpha-synuclein, which has been previously implicated in Parkinson's disease. Previous studies have shown that hyperphosphorylation of the α-synuclein protein on serine 129 is related to this aggregation.


"Identifying the kinases and phosphates that regulate this critical phosphorylation event may ultimately prove beneficial in the development of new drugs that could prevent synuclein dysfunction and toxicity in Parkinson's disease and other synucleinopathies," said Dr. Travis Dunckley, a TGen Assistant Professor and senior author of the study.


Synucleinopathies are neurodegenerative disorders characterized by aggregates of α-synuclein protein. They include Parkinson's, various forms of dementia and multiple systems atrophy (MSA).


The study SMG1 Identified as a Regulator of Parkinson's disease-associated alpha-Synuclein Through siRNA Screening was published today in the journal PLOS ONE.


By using the latest in genomic technologies, Dr. Dunckley and collaborators found that expression of the protein SMG1 was "significantly reduced" in tissue samples of patients with Parkinson's and dementia.


"These results suggest that reduced SMG1 expression may be a contributor to α-synuclein pathology in these diseases," Dr. Dunckley said.


TGen collaborators in this study included researchers from Banner Sun Health Institute and Mayo Clinic Scottsdale.


Tissue samples were provided by the Banner Brain and Body Donation Program. The study was funded by the Arizona Parkinson's Disease Consortium, which includes Mayo Clinic Scottsdale, Sun Health Research Institute, Barrow Neurologic Institute, Banner Good Samaritan Medical Center, Arizona State University, and TGen.


###

The study is available at: http://dx.plos.org/10.1371/journal.pone.0077711.



About TGen



Translational Genomics Research Institute (TGen) is a Phoenix, Arizona-based non-profit organization dedicated to conducting groundbreaking research with life changing results. TGen is focused on helping patients with cancer, neurological disorders and diabetes, through cutting edge translational research (the process of rapidly moving research towards patient benefit). TGen physicians and scientists work to unravel the genetic components of both common and rare complex diseases in adults and children. Working with collaborators in the scientific and medical communities literally worldwide, TGen makes a substantial contribution to help our patients through efficiency and effectiveness of the translational process. For more information, visit: http://www.tgen.org.


Press Contact:

Steve Yozwiak

TGen Senior Science Writer

602-343-8704

syozwiak@tgen.org




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Absence of the SMG1 protein could contribute to Parkinson's and other neurological disorders


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PUBLIC RELEASE DATE:

30-Oct-2013



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Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute



TGen-led study links lack of SMG1 to protein aggregates associated with Parkinson's disease, forms of dementia and multiple systems atrophy



PHOENIX, Ariz. Oct. 30, 2013 The absence of a protein called SMG1 could be a contributing factor in the development of Parkinson's disease and other related neurological disorders, according to a study led by the Translational Genomics Research Institute (TGen).


The study screened 711 human kinases (key regulators of cellular functions) and 206 phosphatases (key regulators of metabolic processes) to determine which might have the greatest relationship to the aggregation of a protein known as alpha-synuclein, which has been previously implicated in Parkinson's disease. Previous studies have shown that hyperphosphorylation of the α-synuclein protein on serine 129 is related to this aggregation.


"Identifying the kinases and phosphates that regulate this critical phosphorylation event may ultimately prove beneficial in the development of new drugs that could prevent synuclein dysfunction and toxicity in Parkinson's disease and other synucleinopathies," said Dr. Travis Dunckley, a TGen Assistant Professor and senior author of the study.


Synucleinopathies are neurodegenerative disorders characterized by aggregates of α-synuclein protein. They include Parkinson's, various forms of dementia and multiple systems atrophy (MSA).


The study SMG1 Identified as a Regulator of Parkinson's disease-associated alpha-Synuclein Through siRNA Screening was published today in the journal PLOS ONE.


By using the latest in genomic technologies, Dr. Dunckley and collaborators found that expression of the protein SMG1 was "significantly reduced" in tissue samples of patients with Parkinson's and dementia.


"These results suggest that reduced SMG1 expression may be a contributor to α-synuclein pathology in these diseases," Dr. Dunckley said.


TGen collaborators in this study included researchers from Banner Sun Health Institute and Mayo Clinic Scottsdale.


Tissue samples were provided by the Banner Brain and Body Donation Program. The study was funded by the Arizona Parkinson's Disease Consortium, which includes Mayo Clinic Scottsdale, Sun Health Research Institute, Barrow Neurologic Institute, Banner Good Samaritan Medical Center, Arizona State University, and TGen.


###

The study is available at: http://dx.plos.org/10.1371/journal.pone.0077711.



About TGen



Translational Genomics Research Institute (TGen) is a Phoenix, Arizona-based non-profit organization dedicated to conducting groundbreaking research with life changing results. TGen is focused on helping patients with cancer, neurological disorders and diabetes, through cutting edge translational research (the process of rapidly moving research towards patient benefit). TGen physicians and scientists work to unravel the genetic components of both common and rare complex diseases in adults and children. Working with collaborators in the scientific and medical communities literally worldwide, TGen makes a substantial contribution to help our patients through efficiency and effectiveness of the translational process. For more information, visit: http://www.tgen.org.


Press Contact:

Steve Yozwiak

TGen Senior Science Writer

602-343-8704

syozwiak@tgen.org




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Source: http://www.eurekalert.org/pub_releases/2013-10/ttgr-aot103013.php
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UN: US says it doesn't, and won't, spy on UN


UNITED NATIONS (AP) — The United Nations said Wednesday it has received assurances from the U.S. government that U.N. communications networks "are not and will not be monitored" by American intelligence agencies. But chief U.N. spokesman Martin Nesirky would not comment on whether the world body had been monitored in the past, as reported recently by the German magazine Der Spiegel.

Nesirky said the United Nations had been in contact with Washington about the reports that surfaced two months ago and has received a U.S. guarantee of no current or future eavesdropping.

"Back in August when these reports first surfaced, we said we would be in touch with the relevant authorities," he said. "And I can tell you that we were indeed in touch with the U.S. authorities. I understand that the U.S. authorities have given assurance that the United Nations communications are not and will not be monitored."

Nesirky would not elaborate on whether spying had taken place and declined to answer related questions. For emphasis, he held up a piece of paper that said: "No comment."

A U.S. official told The Associated Press that "The United States is not conducting electronic surveillance targeting the United Nations headquarters in New York." The official, who was not authorized to be named, spoke on condition of anonymity.

It was not clear whether foreign U.N. missions in New York could be monitored by U.S. intelligence agencies.

Former U.S. Ambassador John Bolton, who held the post at the United Nations from 2005-2006, would not comment on "what may or may not have gone on in the past" because he's no longer in government.

"That said, it seems to me that the United Nations and everybody walking through the U.N. building are perfectly legitimate intelligence targets, and I think any decision by any president to say we are not going to eavesdrop on U.N. headquarters is a mistake," he told the AP.

"There's nothing in the U.S. Constitution that says you may not eavesdrop on the U.N.," Bolton said. "Silence and a deeply emphasized 'No comment' is how you should deal with all these intelligence questions."

Der Spiegel reported that documents it obtained from U.S. leaker Edward Snowden show the National Security Agency secretly monitored the U.N.'s internal video conferencing system by decrypting it last year.

Der Spiegel quoted an NSA document as saying that within three weeks, the number of decoded communications had increased from 12 to 458. Der Spiegel also reported that the NSA installed bugs in the European Union's office building in Washington and infiltrated the EU's computer network.

The United Nations lodged objections. U.N. spokesman Farhan Haq said in August that international treaties protect U.N. offices and all diplomatic missions from interference, spying and eavesdropping.

"The inviolability of diplomatic missions, including the United Nations, has been well-established in international law, and therefore all states are expected to act accordingly," Nesirky said Wednesday.

The 1961 Vienna Convention regulates diplomatic issues and status among nations and international organizations. Among other things, it says a host country cannot search diplomatic premises or seize its documents or property. It also says the host government must permit and protect free communication between the diplomats of the mission and their home country.

However, wiretapping and eavesdropping have been used for decades, most dramatically between the United States and the Soviet Union during the Cold War.

Source: http://news.yahoo.com/un-us-says-doesnt-wont-spy-un-173715063.html
Category: Colleen Ritzer   politico   Nina Davuluri   friday the 13th   brandon jacobs  

Switzerland signs the ELIXIR consortium agreement and contributes €35 million

Switzerland signs the ELIXIR consortium agreement and contributes €35 million


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Contact: Irene Perovsek
irene.perovsek@isb-sib.ch
41-216-924-054
Swiss Institute of Bioinformatics





Switzerland's State Secretary for Education, Research and Innovation, Dr Mauro Dell'Ambrogio, has signed the ELIXIR Consortium Agreement for the establishment of ELIXIR, the European Life science Infrastructure for Biological Information. This brings closer the time when five Member States will have signed, and the Consortium Agreement will enter into force. The Swiss government has committed to investing 35 million over the four-year period from 2013 to 2016. This monetary contribution is mainly provided through financial support to SIB Swiss Institute of Bioinformatics the Swiss ELIXIR Node. However, the experience and expertise of SIB are also an important part of Switzerland's participation. Access to SIB's bioinformatics core resources and many other high-quality services, as well as the benefit of its solid experience in bioinformatics training will be major assets in the launch and success of ELIXIR.


The deluge of data produced by life science researchers thanks to new-generation technologies is a very positive development, given the wealth of information hidden in this data. Our society is constantly being challenged by crucial questions related to food, energy, the environment and, of course, health. Such data is a windfall for researchers provided that both the information and the bioinformatics resources for its analysis are accessible over the long term. ELIXIR is the European consortium, whose aim is to set up and operate a sustainable European infrastructure for biological information to support life science research and its translation to medicine, the environment, the bio-industries and society. This requires international coordination and the assurance of long-term funding.


The International Consortium Agreement signed by Switzerland today is key for the set-up of ELIXIR. Niklas Blomberg, Director of ELIXIR, is "very pleased that Switzerland, a pioneer and one of the world leaders in bioinformatics, is one of the first Member States to ratify the Agreement". Switzerland, which had already signed the Memorandum of Understanding in 2011, has thus confirmed its participation in the project. Research, life sciences and bioinformatics have been strongly supported by the Swiss government for many years, which is one of the reasons why Switzerland currently has a robust bioinformatics infrastructure.


SIB, the Swiss node of ELIXIR, is pleased to lend its support to ELIXIR


Since its inception, SIB, which is celebrating its 15th anniversary this year, has positioned itself as a major contributor to the life sciences. UniProtKB/Swiss-Prot, neXtProt, STRING, SWISS-MODEL are only a few of the core resources that have been created by SIB and are available to the life science research community worldwide. In total, more than 130 resources are accessible through SIB's web portal ExPASy (http://www.expasy.org). SIB, whose infrastructure and research groups are located in the major Swiss Universities and Federal Institutes of Technology, has a long experience in interinstitutional, intercantonal and international collaboration. Training the next generation of bioinformaticians is another of the Institute's roles, and demonstrates how SIB's missions are in tune with those of ELIXIR. According to Ron Appel, Executive Director of SIB, "ELIXIR will give a new dimension to European collaboration and open the door to the future of science".

###


About SIB



SIB Swiss Institute of Bioinformatics is an academic not-for-profit foundation recognized of public utility. It federates bioinformatics activities throughout Switzerland. Its two-fold mission is to provide world-class core bioinformatics resources to the national and international life science research community in key fields such as genomics, proteomics and systems biology, as well as to lead and coordinate the field of bioinformatics in Switzerland. It has a long-standing tradition of producing state-of-the-art software for the life science research community, as well as carefully annotated databases. SIB includes 46 world-class research and service groups, a total of more than 650 scientists, in the fields of proteomics, transcriptomics, genomics, systems biology, structural bioinformatics, evolutionary bioinformatics, modelling, imaging, biophysics, and population genetics in Basel, Bern, Fribourg, Geneva, Lausanne, Lugano and Zurich. SIB expertise is widely appreciated and its services are used by life sciences researchers worldwide.


Contacts:


SIB Swiss Institute of Bioinformatics

Ron Appel, Executive Director

Quartier Sorge - Btiment Gnopode

1015 Lausanne

+41 (0)21 692 40 50




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Switzerland signs the ELIXIR consortium agreement and contributes €35 million


[ Back to EurekAlert! ]

PUBLIC RELEASE DATE:

30-Oct-2013



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Contact: Irene Perovsek
irene.perovsek@isb-sib.ch
41-216-924-054
Swiss Institute of Bioinformatics





Switzerland's State Secretary for Education, Research and Innovation, Dr Mauro Dell'Ambrogio, has signed the ELIXIR Consortium Agreement for the establishment of ELIXIR, the European Life science Infrastructure for Biological Information. This brings closer the time when five Member States will have signed, and the Consortium Agreement will enter into force. The Swiss government has committed to investing 35 million over the four-year period from 2013 to 2016. This monetary contribution is mainly provided through financial support to SIB Swiss Institute of Bioinformatics the Swiss ELIXIR Node. However, the experience and expertise of SIB are also an important part of Switzerland's participation. Access to SIB's bioinformatics core resources and many other high-quality services, as well as the benefit of its solid experience in bioinformatics training will be major assets in the launch and success of ELIXIR.


The deluge of data produced by life science researchers thanks to new-generation technologies is a very positive development, given the wealth of information hidden in this data. Our society is constantly being challenged by crucial questions related to food, energy, the environment and, of course, health. Such data is a windfall for researchers provided that both the information and the bioinformatics resources for its analysis are accessible over the long term. ELIXIR is the European consortium, whose aim is to set up and operate a sustainable European infrastructure for biological information to support life science research and its translation to medicine, the environment, the bio-industries and society. This requires international coordination and the assurance of long-term funding.


The International Consortium Agreement signed by Switzerland today is key for the set-up of ELIXIR. Niklas Blomberg, Director of ELIXIR, is "very pleased that Switzerland, a pioneer and one of the world leaders in bioinformatics, is one of the first Member States to ratify the Agreement". Switzerland, which had already signed the Memorandum of Understanding in 2011, has thus confirmed its participation in the project. Research, life sciences and bioinformatics have been strongly supported by the Swiss government for many years, which is one of the reasons why Switzerland currently has a robust bioinformatics infrastructure.


SIB, the Swiss node of ELIXIR, is pleased to lend its support to ELIXIR


Since its inception, SIB, which is celebrating its 15th anniversary this year, has positioned itself as a major contributor to the life sciences. UniProtKB/Swiss-Prot, neXtProt, STRING, SWISS-MODEL are only a few of the core resources that have been created by SIB and are available to the life science research community worldwide. In total, more than 130 resources are accessible through SIB's web portal ExPASy (http://www.expasy.org). SIB, whose infrastructure and research groups are located in the major Swiss Universities and Federal Institutes of Technology, has a long experience in interinstitutional, intercantonal and international collaboration. Training the next generation of bioinformaticians is another of the Institute's roles, and demonstrates how SIB's missions are in tune with those of ELIXIR. According to Ron Appel, Executive Director of SIB, "ELIXIR will give a new dimension to European collaboration and open the door to the future of science".

###


About SIB



SIB Swiss Institute of Bioinformatics is an academic not-for-profit foundation recognized of public utility. It federates bioinformatics activities throughout Switzerland. Its two-fold mission is to provide world-class core bioinformatics resources to the national and international life science research community in key fields such as genomics, proteomics and systems biology, as well as to lead and coordinate the field of bioinformatics in Switzerland. It has a long-standing tradition of producing state-of-the-art software for the life science research community, as well as carefully annotated databases. SIB includes 46 world-class research and service groups, a total of more than 650 scientists, in the fields of proteomics, transcriptomics, genomics, systems biology, structural bioinformatics, evolutionary bioinformatics, modelling, imaging, biophysics, and population genetics in Basel, Bern, Fribourg, Geneva, Lausanne, Lugano and Zurich. SIB expertise is widely appreciated and its services are used by life sciences researchers worldwide.


Contacts:


SIB Swiss Institute of Bioinformatics

Ron Appel, Executive Director

Quartier Sorge - Btiment Gnopode

1015 Lausanne

+41 (0)21 692 40 50




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Source: http://www.eurekalert.org/pub_releases/2013-10/siob-sst103013.php
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Obama cites early setbacks of Mass. health law


BOSTON (AP) — President Barack Obama chose the site where Massachusetts' health care system became law to promote his signature health insurance program, arguing that the state plan also faced initial setbacks and low enrollment but in time gained popularity and became a success.

"All the parade of horribles, the worst predictions about health care reform in Massachusetts never came true," he said. "They're the same arguments that you're hearing now."

The Massachusetts' law provided the model for the federal health insurance overhaul. Obama spoke in Boston's historic Faneuil Hall, where Massachusetts Republican Gov. Mitt Romney was joined by the late Democratic Sen. Ted Kennedy to sign the state's 2006 health care overhaul bill.

The president pointed to benefits already available under the 3-year-old health care law, including ending discrimination against children with pre-existing conditions and permission to keep young people on their parents' insurance plans until they turn 26.

But he conceded the troubled launch of the open enrollment period that began Oct. 1.

"I am not happy about it," he said.

Underscoring the president's challenge, the HealthCare.gov website was down, because of technical difficulties, during his remarks. Republicans say the current computer dysfunction is more reason to repeal the law, and they're pressing Obama administration officials for an explanation.

Obama also tried to clarify the most recent controversy surrounding the law — the wave of cancellation notices hitting small businesses and individuals who buy their own insurance. Obama repeatedly had vowed that people who liked their insurance would be able to keep it.

The cancellation notices apply to people whose plans changed after the law was implemented or don't meet new coverage requirements. The president said those changes ensure that all Americans are able to get quality coverage.

He said that because of government subsidies, most people who must get new policies will pay less than they do now. But he acknowledged that "a fraction of Americans with higher incomes" will likely pay more.

Romney took issue with Obama's characterization of the Massachusetts health care law. In a statement, he said "had President Obama actually learned the lessons of Massachusetts health care, millions of Americans would not lose the insurance they were promised they could keep, millions more would not see their premiums skyrocket and the installation of the program would not have been a frustrating embarrassment." During the 2012 presidential campaign, Romney had pledged to work for the repeal of Obama's health care law if elected.

Obama, who lived in Boston while a student at Harvard University, was in town for a World Series game day, but his spokesman said he didn't plan to make a side trip to Fenway Park, mindful of the impact his security entourage has on the public.

While in Boston, Obama also spoke at a fundraiser for House Democrats, where about 60 people dined on Spanish-influenced fare, followed by Red Sox cookies honoring the World Series game being played in town the same night.

Invoking the school shooting in nearby Connecticut and the Boston Marathon bombing, Obama said it had been a "challenging year." He said he had hoped the tragedies would presage a new spirit of cooperation in Congress, but Americans got obstruction, instead.

"However low people's estimations were of Washington before the shutdown," Obama said, "they're lower now."

___

Associated Press writer Steve LeBlanc in Boston contributed to this report.

___

Follow Nedra Pickler on Twitter at https://twitter.com/nedrapickler

Source: http://news.yahoo.com/obama-cites-early-setbacks-mass-health-law-224529968--finance.html
Category: walking dead   Nothing Was The Same Leak   powerball numbers   michael jackson   Demi Lovato  

Lenovo hires Kutcher to design, pitch new tablet

SAN FRANCISCO (AP) — Computer-maker Lenovo has hired tech-savvy actor Ashton Kutcher to help design and pitch its latest line of tablets, dubbing the Hollywood star a "product engineer" who can bring his ideas along with his image.

It's the latest tech foray for the "Two and a Half Men" performer who recently starred in a biopic about innovative giant Steve Jobs and has invested venture capital in more than a dozen Silicon Valley startups.

The deal was announced Tuesday at a Lenovo live-streamed event in Los Angeles. Lenovo's first video advertisements for the new Yoga Tablet feature Kutcher acting as a product tester in his boxers, a spacesuit and aboard an airplane.

The company said Kutcher will do more than just advertise.

"This partnership goes beyond traditional bounds by deeply integrating him into our organization as a product engineer as we look at developing the next wave of products," said Lenovo spokesman David Roman.

Kutcher — who in recent years has appeared in ads for snack chips and cameras — said of Lenovo, "Entrepreneurship is part of their DNA, and I couldn't ask for a better fit."

Financial terms of the deal were not disclosed.

Lenovo, with headquarters in Beijing and in Research Triangle Park, N.C., acquired IBM's computer business in 2005 and became the world's top PC-maker ahead of HP in the third quarter. But, like other manufacturers, it has struggled with waning consumer demand for desktop and laptop models.

It's one of several Asian tech companies seeking to loosen Apple's grip on China's tablet market with less expensive Android models.

Associated PressSource: http://hosted2.ap.org/APDEFAULT/495d344a0d10421e9baa8ee77029cfbd/Article_2013-10-30-Kutcher%20Sells%20Tech/id-afca0308f2644cf8be8cedc8d5d58480
Tags: Blackfish   notre dame football   darren sproles   trent richardson   Eydie Gorme  

Concerns raised about security of health website

Health and Human Services Secretary Kathleen Sebelius gestures while testifying on Capitol Hill in Washington, Wednesday, Oct. 30, 2013, before the House Energy and Commerce Committee hearing on the difficulties plaguing the implementation of the Affordable Care Act. The Obama Administration claims the botched rollout was the result of contractors failing to live up to expectations – not bad management at HHS. As the public face of President Barack Obama's signature health care program, Sec. Sebelius has become the target for attacks over its botched rollout with Republicans, and even some Democrats, calling for her to resign. (AP Photo/J. Scott Applewhite)







Health and Human Services Secretary Kathleen Sebelius gestures while testifying on Capitol Hill in Washington, Wednesday, Oct. 30, 2013, before the House Energy and Commerce Committee hearing on the difficulties plaguing the implementation of the Affordable Care Act. The Obama Administration claims the botched rollout was the result of contractors failing to live up to expectations – not bad management at HHS. As the public face of President Barack Obama's signature health care program, Sec. Sebelius has become the target for attacks over its botched rollout with Republicans, and even some Democrats, calling for her to resign. (AP Photo/J. Scott Applewhite)







Health and Human Services Secretary Kathleen Sebelius is surrounded by photographers on Capitol Hill in Washington, Wednesday, Oct. 30, 2013, prior to testifying before the House Energy and Commerce Committee hearing on the difficulties plaguing the implementation of the Affordable Care Act. Sebelius, President Barack Obama's top health official faced tough questioning by a congressional committee Wednesday that will demand she explain how the administration stumbled so badly in its crippled online launch of the president's health care overhaul. (AP Photo/ Evan Vucci)







Health and Human Services Secretary Kathleen Sebelius is sworn in on Capitol Hill in Washington, Wednesday, Oct. 30, 2013, by House Energy and Commerce Committee Chairman Rep. Fred Upton, R-Mich., prior to testifying before the committee's hearing on the difficulties plaguing the implementation of the Affordable Care Act. Sebelius, President Barack Obama's top health official faced tough questioning by a congressional committee Wednesday that will demand she explain how the administration stumbled so badly in its crippled online launch of the president's health care overhaul. (AP Photo/ Evan Vucci)







Health and Human Services Secretary Kathleen Sebelius is sworn in on Capitol Hill in Washington, Wednesday, Oct. 30, 2013, prior to testifying before the House Energy and Commerce Committee hearing on the difficulties plaguing the implementation of the Affordable Care Act. President Barack Obama's top health official faced tough questioning by a congressional committee Wednesday that will demand she explain how the administration stumbled so badly in its crippled online launch of the president's health care overhaul. (AP Photo/ J. Scott Applewhite)







(AP) — Defending President Barack Obama's much-maligned health care overhaul in Congress, his top health official was confronted Wednesday with a government memo raising new security concerns about the trouble-prone website that consumers are using to enroll.

The document, obtained by The Associated Press, shows that administration officials at the Centers for Medicare and Medicaid Services were concerned that a lack of testing posed a potentially "high" security risk for the HealthCare.gov website serving 36 states. It was granted a temporary security certificate so it could operate.

Security issues are a new concern for the troubled HealthCare.gov website. If they cannot be resolved, they could prove to be more serious than the long list of technical problems the administration is trying to address.

"You accepted a risk on behalf of every user...that put their personal financial information at risk," Rep. Mike Rogers, R-Mich., told Health and Human Services Secretary Kathleen Sebelius during questioning before the House Energy and Commerce Committee. "Amazon would never do this. ProFlowers would never do this. Kayak would never do this. This is completely an unacceptable level of security."

Sebelius countered that the system is secure, even though the site has a temporary certificate, known in government parlance as an "authority to operate." Sebelius said a permanent certificate will only be issued once all security issues are addressed.

Added spokeswoman Joanne Peters: "When consumers fill out their online...applications, they can trust that the information they're providing is protected by stringent security standards and that the technology underlying the application process has been tested and is secure. Security testing happens on an ongoing basis using industry best practices."

A security certificate is required before any government computer system can process, store or transmit agency data. Temporary certificates are allowable, but under specific circumstances.

Earlier, the secretary said she's responsible for the "debacle" of cascading problems that overwhelmed the government website intended to make shopping for health insurance clear and simple.

"Hold me accountable for the debacle," Sebelius said during a contentious hearing. "I'm responsible."

Sebelius is promising to have the problems fixed by Nov. 30, even as Republicans opposed to Obama's health care law are calling in chorus for her resignation. She told the committee that the technical issues that led to frozen screens and error messages are being cleared up on a daily basis.

Addressing consumers, Sebelius added, "So let me say directly to these Americans, you deserve better. I apologize."

The Sept. 27 memo to Medicare chief Marylin Tavenner said a website contractor wasn't able to test all the security controls in one complete version of the system.

"From a security perspective, the aspects of the system that were not tested due to the ongoing development, exposed a level of uncertainty that can be deemed as a high risk for the (website)," the memo said.

It recommended setting up a security team to address risks, conduct daily tests, and a full security test within two to three months of going live.

HealthCare.gov was intended to be the online gateway to coverage for millions of uninsured Americans, as well those who purchase their policies individually. Many people in the latter group will have to get new insurance next year, because their policies do not meet the standards of the new law.

Sebelius' forthright statement about her ultimate accountability came as she was being peppered with questions by Rep. Marsha Blackburn, R-Tenn., about who was responsible. It was Blackburn who introduced the term "debacle."

Rep. Henry Waxman of California, the ranking Democrat on the committee, scoffed at Republican "oversight" of a law they have repeatedly tried to repeal.

"I would urge my colleagues to stop hyperventilating," said Waxman. "The problems with HealthCare.gov are unfortunate and we should investigate them, but they will be fixed. And then every American will have -- finally have access to affordable health insurance."

Throughout the hearing, Sebelius was respectful and poised, often addressing lawmakers as "sir" or "congresswoman." She kept her cool as some lawmakers repeatedly cut off her answers. But she did not shy a few times from tersely interjecting her views while a member was speaking.

The standing-room-only hearing room was silent when she swore an oath to tell the truth and began her statement. "I apologize," she told the rapt committee.

Sebelius faced questions about problems with the website as well as a wave of cancellation notices hitting individuals and small businesses who buy their own insurance.

Lawmakers also want to know how many people have enrolled in plans through the health exchanges, a number the Obama administration has so far refused to divulge, instead promising to release it in mid-November.

On Tuesday, Medicare chief Marilyn Tavenner was questioned for nearly three hours by members of the House Ways and Means Committee who wanted to know why so many of their constituents were getting cancellation notices from their insurance companies.

The cancellations problem goes to one of Obama's earliest promises about the health law: You can keep your plan if you like it. The promise dates back to June 2009, when Congress was starting to grapple with overhauling the health care system to cover uninsured Americans.

As early as last spring, state insurance commissioners started giving insurers the option of canceling existing individual plans for 2014, because the coverage required under Obama's law is significantly more robust. Some states directed insurers to issue cancellations. Large employer plans that cover most workers and their families are unlikely to be affected.

The law includes a complicated "grandfathering" system to try to make good on Obama's pledge. It shields plans from the law's requirements provided the plans themselves change very little. Insurers say it has proven impractical. The cancellation notices are now reaching policyholders.

Tavenner blamed insurance companies for cancelling the policies and said most people who lose coverage will be able to find better replacement plans in the health insurance exchanges, in some cases for less money.

Associated PressSource: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-10-30-Health%20Overhaul-Problems/id-463dace01eff4c5b858b7cf28ec8b5d4
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